RMTC FAQ

Q: How were the thresholds developed?
A" Some of the thresholds are based upon historical data and research (e.g., phenylbutazone, flunixin meglumine, and furosemide). The majority of the thresholds, however, were developed using research studies funded by the RMTC or studies shared with the RMTC from similar international studies. In the majority of the RMTC studies, between 16 and 22 horses were used. First, the subject medication was administered at clinically relevant dosages based on either manufacturer’s recommendations or input from clinicians and/or veterinary pharmacologists. Once a medication was administered researchers collected blood, and in some cases urine, at predetermined times post administration. After the samples were collected the analytic laboratory analyzed the samples using a validated method and provided their results to the RMTC. Most of these studies have been published or are in the process of being published in peer-reviewed journals.

For non-historical thresholds, RMTC then used that data and applied a 95/95 tolerance interval calculation to the data. The 95/95 tolerance interval is a robust statistical analysis used by the European Agency for the Evaluation of Medicinal Products. It accounts for the variability of the data as well as the number of horses used in the study. A full explanation of the analysis can be found here.

The AJC is a staunch supporter of the efforts of the Racing Medication & Testing Consortium. #CleanRacing ... Read MoreSee Less

AJC ALERT!

Below is the nomination form for the Sheikh Zayed bin Sultan Al Nahyan Crown Jewel race to be held November 9, 2018 in Abu Dhabi. All nominations are due via email by October 14, 2018. If you would like your horse to be considered for an invitation to this race, please be sure to submit your nomination in a timely manner. ... Read MoreSee Less