RMTC Spotlight

Q: Why can’t I use Depo-Medrol (methylprednisolone acetate) and Vetalog (triamcinolone acetonide) intramuscularly (IM), subcutaneously (SQ), or in the sacroiliac space?

A: There is no prohibition against using any of the corticosteroids on the CTS list IM, SQ, or in the sacroiliac space. However, corticosteroids formulated as fat soluble esters (e.g., methylprednisolone acetate) take an extremely long time (up to several months) to fall below the regulatory threshold after certain routes of administration. Corticosteroids without an ester (e.g., isoflupredone) or those formulated as highly water soluble esters (e.g., dexamethasone sodium phosphate) will take less time – but will still likely take more than the recommended withdrawal time for an intra-articular (IA) or intravenous (IV) dose. Similarly, an IA injection that inadvertently ends up outside of the articular space can take longer to clear than the withdrawal guidelines suggest. #RMTCFAQ #CleanRacing

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